Effects of Fluid Loading with Water, Normal Saline, Coffee and Coke on Urinary Output, pH and Specific Gravity in Young Healthy Undergraduate Students
doi.org/10.26538/tjnpr/v4i7.12
Keywords:
Fluid loading,, Homeostatic function,, Diuresis,, Coffee,, Coke.Abstract
Balance of water and electrolyte is an important homeostatic function of the kidneys. Their excretion depends on various factors such as, state of hydration, plasma osmolarity, etc. There are rare reports on diuretic effect of Coffee and Coke on some urinary parameters. Hence, the study is aimed at investigating the effect of Water, Normal Saline, Coffee and Coke in young healthy undergraduate students. A total of forty (40) randomly selected, healthy undergraduate students were recruited for this study. They were randomly divided into four groups. One liter (1 L) of Water, Normal Saline, Coffee and Coke were administered on different days to the same subjects. The subjects were made to void their bladders before ingesting these substances and the urine samples collected were taken as control sample at the time zero (T = 0). Thereafter, all the subjects emptied their bladders and their urine was collected at 30 minutes interval for 150 minutes. The urinary output, pH and specific gravity were determined. The results showed that urine output for Water, Coffee and Coke produced diuresis while Normal Saline did not. The reductions in specific gravity and pH of urine also accompanied these diuretic effects.
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