Evaluation of Antioxidant and Antimicrobial Activities of Stachys Leaves Extract
http://www.doi.org/10.26538/tjnpr/v6i9.22
Keywords:
GC-MS profile, Antimicrobial, Antioxidants, StachysAbstract
The genus Stachys L. (Lamiaceae) includes about 300 species located in temperate and tropical regions across the world Mediterranean, Asia, America and southern Africa. Several species of this genus are extensively used in various traditional medicines of special pharmacological interest are considered the anti-inflammatory, antioxidant, analgesic, anxiolytic and antidepressant activity. The aim of this study was to evaluate the bioactive compounds, antioxidants and antimicrobial activity of Stachys leaves extract. The antioxidant activity was determined by measuring total phenolic content (TPC) and 2,2-diphenyl-1-picrylhydrazyl (DPPH). Methanol extracts of Stachys leaves extract and evaluated for its antimicrobial activity. The antibacterial activity was assessed using paper disc method against two bacteria namely Staphylococcus aureus and E. coli. Showed that leaves extracts presented the highest phenolic
compounds content for both species. Furthermore, GC-MS analysis allowed the identification of 37 bioactive compounds regardless of Stachys leaves extract. Leaves extract of Stachys possessed the highest total phenol content and antioxidant activity (DPPH). The antimicrobial tests showed that leaves extracts of Stachys exhibited the highest activity against two bacterial strains (Staphylococcus aureus and Escherichia coli). The studied leaves of Stachys is considered an excellent source of natural bioactive molecules that could be an interesting material for medicinal and food purposes.
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