External Application of Traditional Chinese Medicine for Fat Liquefaction in Abdominal Incision: A Systematic Review and Meta-Analysis

Lian Liu1, Song Wei Su2, Fan Li1, Siping Yu1, Qiuxia Liu1, Yanfang Huang, Hong Y. Sun1*
1Nursing School, Southwest Medical University, No. 3, 319 Section of Zhong Shan Road, Jiangyang District, Luzhou 646000, China.
2Basic school, Guangzhou University of Chinese Medicine, No. 232, Eastern outer ring road of Guangzhou University Island, Panyu District, Guangzhou, 520006, China.
Corresponding Author: [email protected]; Tel: 86-136-8820-6787
Recieved Date: September 09, 2017; Accepted Date: September 28, 2017; Published Date: 05 October 2017
Citation: Liu L, Su SW, Li F, Yu S, Liu Q, Huang Y, Sun HY. External Application of Traditional Chinese Medicine for Fat Liquefaction in Abdominal Incision: A Systematic Review and Meta-Analysis. Tropical Journal of Natural Product Research 2017; 1(4):137-152. doi.org/10.26538/tjnpr/v1i4.2 https://doi.org/10.26538/tjnpr/v1i4.2
Copyright: © 2017 Liu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
ABSTRACT

Fat liquefaction in the abdominal incision (FLAI) is a common malignant complication with limitations of current treatments. Given the poor prognosis associated with an abdominal incision, many patients seek additional therapies that may improve the quality of life. Several external applications of traditional Chinese medicine (EA-TCM) have been evaluated in clinical trials, but fewer are known about them outside of China. The objective of this study is to evaluate the effectiveness of EA-TCM for prevention and treatment of fat liquefaction in abdominal incision. Fifty-four (54) of seven thousand three hundred and sixty-three (7363) randomized controlled trials (RCTs) in seven electronic databases met inclusion criteria. Two researchers independently selected articles, extracted data, assessed quality, and cross-checked the results. Revman 5.3.1 was used to analyze the results. The meta-analysis indicated that compared with conventional therapies alone or EA-TCM combined with conventional therapy. EA-TCM could elevate total effectiveness rate in treatment and preventing FLAI, reducing the incidence of FLAI; decreasing healing time of FLAI and average hospitalization time without serious adverse effects. Therefore, clinicians may consider EA-TCM as a viable complementary and alternative medicine for FLAI. However, a clinical recommendation is not warranted due to the low methodology quality. Multi-center and high-quality RCTs with large sample sizes are needed.

Keywords: External Application, Traditional Chinese Medicines, Prevention Treatment Fat Liquefaction
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