Hyptis suaveolens Extract Exhibits Larvicidal Activity Against Anopheles gambiae Larvae

Jeremiah I. Abok1*, Akwashiki Ombugadu2, Gladys A. Angbalaga3
1Department of Chemistry, Federal University Lafia, Nasarawa State, Nigeria.
2Department of Zoology, Federal University Lafia, Nasarawa State, Nigeria.
3Department of Microbiology, Federal University Lafia, Nasarawa State, Nigeria

Corresponding Author: [email protected] ; Tel: +2348065402381
Recieved Date: January 28, 2018; Accepted Date: May 08, 2018; Published Date: 10 May 2018
Citation: Abok JI, Ombugadu A, Angbalaba GA. Hyptis suaveolens Extract Exhibits Larvicidal Activity Against Anopheles gambiae Larvae. Trop J Nat Prod Res. 2018; 2(5):245-249.   https://doi.org//10.26538/tjnpr/v2i5.8
Copyright: © 2018 Abok et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
ABSTRACT

Hyptis suaveolens (Lamiaceae) is traditionally used to repel insects. The aim of this study was to determine the larvicidal activity of dichloromethane aerial part extract of H. suaveolens against 4th instar Anopheles gambiae (Diptera: Culicidae) larvae by establishing dose response of the extracts, determining the lethal concentrations (LC50 and LC90) of the extracts and the efficacy of the plant as a mosquito larvicide following the World Health Organization guidelines for laboratory testing of mosquito larvicides. Two samples of the aerial parts were collected and used for the test; sample Z1 was collected in the morning and sample Z2 in the afternoon. Concentrations ranging from 10 - 100 mg/mL of the extract were used. The results showed that there is a very high significant difference between the two samples in relation to the concentrations (df = 4, P < 0.0001). The larvae were resistant at 24th hour and at 48th hour but became susceptible to the extracts at 72nd hour with 99% and 97% mortality rates with both samples. There was significant difference in mortality rates between the two samples (P < 0.05). LC50 at 72nd hour for Z1 and Z2 was 3.51 mg/mL. LC90 at 72nd hour for Z1 was 1.52 mg/mL and 33.47 mg/mL for Z2. The result of this study indicates that H. suaveolens possesses larvicidal properties and supports its traditional application as a repellant/insecticide. Thus, the plant extract could be applied to mosquito breeding sites as a measure to control malaria vector, particularly A. gambiae.

Keywords: Hyptis suaveolens, Mosquito larvicide, Anopheles gambiae, Malaria.
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ISSN: 2616-0684 (Print)
ISSN: 2616-0692 (Online)
DOI: 10.26538/tjnpr
ISI Impact Factor: 0.562
Index Copernicus Value (ICV) for 2017: 59.83

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