A New Biflavonoid Glycoside from the Leaves of Ziziphus mucronata Willd. (Rhamnaceae)

Musa S. Abdullahi¹*, Muhammad A. Musa¹, Ismail M. Abdullahi², Mohammed Y. Sani¹, Sadiya H. Hassan¹, Jamilu Yau³

¹Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria.

²Department of Pharmaceutical and Medicinal Chemistry, Usmanu Danfodiyo University, Sokoto, Nigeria.

³Department of Pharmacology and Therapeutics, Ahmadu Bello University, Zaria, Nigeria.

Corresponding Author: [email protected]; Tel: +234 803 616 2484

Recieved Date: March 05, 2018; Accepted Date: April 04, 2018; Published Date: 07 April 2018

Citation: Abdullahi SM, Musa AM, Abdullahi MI, Sani YM, Hassan HS, Yau J. A New Biflavonoid Glycoside from the Leaves of Ziziphus mucronata Willd. (Rhamnaceae). Trop J Nat Prod Res. 2018; 2(4):167-170.  https://doi.org//10.26538/tjnpr/v2i4.3

Copyright: © 2018 Abdullahi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

ABSTRACT

A new compound was isolated from the n-butanol fraction of the crude methanol extract of the leaves of Ziziphus mucronata, a plant that is widely used in ethnomedicine to treat inflammation, diarrhoea, tumour, cough, sores, asthma, measles, fever, infections and urinary problems, amongst numerous indications. The isolation of the compound was carried out by a combination of silica gel column and sephadex gel filtration chromatography and the structure was elucidated with the help of UV, IR, and 1D, 2D - 1H and 13C NMR spectroscopic analysis. The compound, a glycoside biflavonoid, was established as bis (quercetin 3-O-?-D-glucopyranoside). The compound might be responsible for some of the observed biological activities of the plant Ziziphus mucronata.