Phytochemical Profile and Antioxidant Activity of Hydroalcoholic Extracts of Corynaea crassa Hook. f (Balanophoraceae) 

Alexandra J. López-Barrera1*, Migdalia Miranda-Martínez2, Yamilet I. Gutiérrez-Gaitén3
1Department of Pharmacy, Faculty of Chemical Sciences. Universidad de Guayaquil. Guayaquil-Ecuador. ORCID:0000-0002-7269-6305.
2Department of Chemical and Environmental Sciences. Faculty of Natural Sciences and Mathematics. Escuela Superior Politécnica del Litoral. Guayaquil. Ecuador. ORCID:0000-0002-6228-1818.
3Department of Pharmacy. Institute of Pharmacy and Food. Universidad de La Habana. Cuba. ORCID:0000-0002-8885-4849.

Corresponding Author: [email protected]; Tel: 5932970481
Recieved Date: 21 February 2021; Accepted Date: 22 August 2021; Published Date: 03 September
Citation: López-Barrera AJ, Miranda-Martínez M, Gutiérrez-Gaitén YI. Phytochemical Profile and Antioxidant Activity of Hydroalcoholic Extracts of Corynaea crassa Hook. f (Balanophoraceae). Trop J Nat Prod Res. 2021; 5(8):1340-1347.
© 2021 López-Barrera  et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Corynaea crassa Hook is a hemiparasitic plant distributed in many regions of America. It has traditionally been ascribed to have aphrodisiac and antimicrobial activities. The objective of this research is to analyze the chemical composition and antioxidant activity of hydroalcoholic extracts of C. crassa from Ecuador and Peru. The whole plant was used for the preparation of the extract. The extracts were made by percolation with 80% ethanol, and the chemical composition was evaluated by ultraviolet-visible (UV/VIS), infrared (IR) spectroscopy and Liquid Chromatography-Mass Spectrometry (LC-MS). The quantification of phenols was done by using the Folin-Ciocalteu method, the flavonoids were quantified by using the aluminum chloride method. The antioxidant activity was tested by Ferric reducing antioxidant power (FRAP), 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2’-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) assays. UV/VIS spectroscopy of the extracts revealed a similar spectral appearance, which denoted the presence of flavonoids and an IR profile characteristic of phenolic compounds, with coincident bands between the extracts but different in intensity and width. Phenols and flavonoids were higher for the Ecuadorian plant extract. The LC-MS study detected catechin, quercetin glycoside, and a flavanone glycoside, for the first time. It was shown that the antioxidant capacity of extracts was similar or superior to the tested substances (Vitamin C and Trolox), with the activity of the Ecuadorian extract being higher. The study of the chemical composition and antioxidant properties of C. crassa, has given credence to the use of the plant in traditional medicine.

Keywords: Corynaea crassa, Phytochemical, Antioxidant, Ecuador, Peru.
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ISSN: 2616-0684 (Print)
ISSN: 2616-0692 (Online)
DOI: 10.26538/tjnpr
Index Copernicus Value (ICV) for 2017: 59.83
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