Inhibitory Effects of Jasminum subtriplinerve Extracts on Nitric Oxide Production and Antioxidant Activity: Influence of Plant Parts and Cultivation Locations in Central Vietnam

Authors

  • Nguyen Duy Ngoc Tan University of Agriculture and Forestry, Hue University, 102 Phung Hung, Hue 530000, Vietnam.
  • Tran Minh Duc University of Agriculture and Forestry, Hue University, 102 Phung Hung, Hue 530000, Vietnam.
  • Tran Nam Thang University of Agriculture and Forestry, Hue University, 102 Phung Hung, Hue 530000, Vietnam.
  • Nguyen Ho Lam Institute of Socio-Economic Development - Hue University, 07 Ha Noi, Hue 530000, Viet Nam.
  • Thanh Pham Department of Biology, University of Education, Hue University, 34 Le Loi, Hue 530000, Vietnam.

DOI:

https://doi.org/10.26538/tjnpr/v8i6.16%20

Keywords:

antioxidant, anti-inflammatory, DPPH, NO, Jasminum subtriplinerve

Abstract

Jasminum subtriplinerve, a Southeast Asia medicinal plant, is traditionally used in Vietnam for its anti-inflammatory, pain-relieving, and antioxidant activity. This study investigates the potential of J. subtriplinerve extracts from the leaf and stem, green fruit, and ripe fruit (obtained from different biological cultivation locations) to inhibit nitric oxide (NO) production and scavenge DPPH radicals. Results reveal significant variations in IC50 values among different plant parts and cultivation locations. The results show that the leaf and stem extracts demonstrated the most potent inhibition of NO production, with the lowest IC50 value observed in Dong Giang (72.46 μg/mL). Conversely, the green and ripe fruit extracts showed weak inhibitory effects, with IC50 values exceeding 90 μg/mL in most cases. Furthermore, analysis of scavenging activity against free radicals using DPPH assay showed similar trends, with the leaf and stem extract exhibiting more potent inhibitory activities than fruit extracts. SC50 values for LS extracts ranged from 36.83 to 50.95 μg/mL. In contrast, GF and RF extracts exhibited weak antioxidant activity, SC50 values exceeding 60 μg/mL, and, in some cases, negligible biological activity (>100 μg/mL). These findings underscore the importance of considering both the plant part and the cultivation location when evaluating the efficacy of J. subtriplinerve extracts in modulating NO production and antioxidant activity.  

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Published

2024-06-29

How to Cite

Tan, N. D. N., Duc, T. M., Thang, T. N., Lam, N. H., & Pham, T. (2024). Inhibitory Effects of Jasminum subtriplinerve Extracts on Nitric Oxide Production and Antioxidant Activity: Influence of Plant Parts and Cultivation Locations in Central Vietnam. Tropical Journal of Natural Product Research (TJNPR), 8(6), 7441–7446. https://doi.org/10.26538/tjnpr/v8i6.16