Dodoneine, its Bicyclic Lactone and a Dihydroxyl-lupeol Palmitate from Tapinanthus globiferus
doi.org/10.26538/tjnpr/v6i6.20
Keywords:
Tapinanthus globiferus, Dodoneine, Dodoneine bicyclolactone, Lupeol palmitate, MistletoeAbstract
Tapinanthus globiferus is a mistletoe plant that is used in traditional medicines throughout equatorial Africa. A chloroform extract of aerial parts of the mistletoe plant epiphytic to a Parkia biglobosa tree was fractionated using silica gel column chromatography, resulting in the isolation of three compounds identified as 7, 15-dihydroxy-lup-20-(29)-ene-2--palmitate, (R)-6-[(S)-2-hydroxy-4-(4-hydroxyphenyl) butyl]-5, 6-dihydropyran-2-one (Dodoneine) and (1R,5S,7S)-7-[2-(4-hydroxyphenyl)ethyl]-2,6-dioxabicyclo[3.3.1]nonan-3-one (Dodoneine bicyclic lactone). Their structures were determined using NMR and mass spectroscopic methods, as well as comparisons to the literature. This is the first report on the isolation of these compounds from Tapinanthus globiferus. xxxxxxxxxxxxxxxxxxxx
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