Review on Effect of Medicinal Plants on Female Reproductive System
http://www.doi.org/10.26538/tjnpr/v7i3.1
Keywords:
hematological, rheumatoid arthritis, Ayurvedic preparation, Vata Gajendra SinghaAbstract
Vata Gajendra Singha (VGS), an Ayurvedic preparation, is used in traditional medicine to treat rheumatoid arthritis in the rural population. The effect of chronic administration of Vata Gajendra Singha (VGS) on the hematological parameters was studied. The acute test of VGS recorded no death, even at the highest dose of 80 ml/ Kg body weight. During chronic testing, the animals were divided into three groups. The first two groups were given VGS preparation at a low dose of 50 mg/kg and a high dose of 400 mg/kg for 28 days, while the third group that served as the control received water for the same period. After 28 days of chronic administration of the VGS preparation, some hematological parameter changes were noted. There were notable changes in the percentage of neutrophils, lymphocytes, Mean Corpuscular Hemoglobin, and platelets attributed on the high and low dosage of Vata Gajendra Singha. These hematological parameters are some important factors related to a variety of disease conditions. Vata Gajendra Singha
negatively affect some hematological parameters abnormally in treated rats and should not be administered chronically at a higher dose.
References
Vos T, Allen C, Arora M, Barber RM, Bhutta ZA, Brown A (GBD 2015 Disease and Injury Incidence and Prevalence Collaborators) (October 2016). "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1545–1602.
Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. "Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010". Lancet. 2012; 12:380 (9859): 2095–128.
“Handout on Health: Rheumatoid Arthritis”. National Institute of Arthritis and Musculoskeletal and Skin Diseases. August 2014. Retrieved 2 July 2015.[online]. Available from: https://www.niams.nih.gov/health-topics/rheumatoidarthritis
GBD 2013 Mortality and Causes of Death Collaborators. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015;385(9963):117-71.
van Delft ETAM, Jamal M, den Braanker H, Kuijper TM, Hazes JMW, Lopes Barreto D, Weel-Koenders AEAM. A systematic review on time trend incidence of rheumatoid arthritis in outpatient rheumatology clinics. Front Med (Lausanne). 2022; 9:933884.
Sikder MM, Zulfiquar TN, Chowdhury IH, Akter K, Asha UH, Haque E, Chakraborty P, Choudhuri MSK. Preclinical Lipid Profile Studies of a Classical Ayurvedic Preparation “Siddha Makardhwaja (SMD)” after Chronic Administration to Male Sprague-Dawley Rats. Biol Med (Aligarh) 2018;10(3):439.
Mahbub MR, Sikder MM, Sony TA, Jahan NN, Faruque MO, Zaman T, Nawar A, Choudhuri MSK. Effect of Pijusaballi Rasa on Thyroid Hormones in Sprague-Dawley Rats. Biol Med (Aligarh) 2020;12(3):467
Anonymous. Bangladesh National Formulary of Ayurvedic Medicine 1992 (Approved by the Government of Bangladesh vide Ministry of Health and Family Welfare Memo No. Health-1/Unani-2/89/(Part-1) 116 dated 3-6-1991). National Unani and Ayurvedic Formulary Committee Bangladesh Board of Unani and Ayurvedic Systems of Medicine, 38, Bangabandhu Avenue, Dhaka-1000. (Second ed.): 2011b. [ISBN 978-984-33-3254-7].
Anonymous (2011) Bangladesh National Formulary of Ayurvedic Medicine 1992 (Approved by the Government of Bangladesh vide Ministry of Health and Family Welfare Memo No. Health-1/Unani-2/89/(Part-1) 116 dated 3-6- 1991). National Unani and Ayurvedic Formulary Committee Bangladesh Board of Unani and Ayurvedic Systems of Medicine, 38, Bangabandhu Avenue, Dhaka-1000 (Second ed. 2011).
Anonymous. Hand book of Ayurvedic and herbal medicines with formulae: with directory of manufacturers and suppliers of plants, equipment and machineries, packaging materials and raw materials suppliers. Engineers India Research Institute, Delhi, XVIII: 1978; 382.
Anonymous. Handbook of Domestic Medicine and Common Ayurvedic Remedies. Central Council for Research in Ayurveda and Siddha., New Delhi, 1978(reprint 2005). 538 p.
Anonymous. Classical Ayurvedic Prescriptions for Common Diseases (Only for registered ayurvedic medical
practitioners). Central Council for Research in Ayurveda and Siddha. Department of AYUSH, Ministry of Health &
Family Welfare Government of India, New Delhi. 2010. 149 p.
Anonymous. Ayurvedic Formulary of India. The Government of India, New Delhi. Vol I, part 3 2011. 710 p.
Pandey G. Bhaisajya Ratnavali, text with English commentary and supplements. Banaras Ayurveda Series 8,
Chowkhamba Sanskrit Series Office, Varanasi. 2005; 1(28):740.
OECD. Guideline (425) for the testing of chemicals, Guidance document on acute oral toxicity, Environmental Health and Safety Monograph Series on Testing and Assessment: 2008; 1-27.
Stevens KR, Gallo MA. Practical consideration in the conduct of chronic toxicity studies, Principles and Methods of Toxicology, 2nd edn. Chap. VIII: 1989.
Ringler H, Dabich L. Hematology and clinical biochemistry. In: The Laboratory Rat Biology and Disease [Baker HL ed]. American College of Laboratory Animal Medicine Series Academic Press: 1979.
Wolford ST, Schoer RA, Gohs FX, Gallo PP. Reference range database for serum chemistry and haematology values in laboratory animals. J Tox Environ Health, 1986; 18: 161- 88.
Tatsumi N, Tsuda I, Furota A, Takubo T , Hayashi M , Matsumoto H, Principle of Blood Cell Counter-Development of Electric Impedance Method. Sysmex J Int. 1999; 9: 8-20
van Kampen EJ, Zijlstra WG. Standardization of hemoglobinometry II. The hemiglobincyanide method. Clinica Chimica Acta, 1961; 6(4): 538–44
Greer JP, Arber DA, Glader B, List AF , Means RT Jr., Paraskevas F, Rodgers GM, Foerster J, Wintrobe's Clinical Hematology. 13th ed . 2014. 4 p.
Diem KL. Clenter. Scientific Tables, 7th ed. Geigy Pharmaceuticals, Basel, Switzerland: 1970. 712 p.
Curry CV, Hermelin D, Medscape (Online), 2022 [June 13]. Available from: https://emedicine.medscape.com/article/2098635- overview#a2
Girling JH. “An automatic platelet counting technique”. The Journal of medical laboratory technology. 1962; 19: 168–73. PMID 13898919.
Westergren A. Diagnostic tests: the erythrocyte sedimentation rate range and limitations of the technique. Triangle. 1957; 3(1): 20–5.
Sikder MM, Chakraborty P, Mahbub MR, Zulfiquar TN, Neon MN, Saha N, Chowdury IH, Choudhuri MSK. Preclinical hematological profile studies of an ayurvedic medicine “Siddha Makardhwaja” after chronic administration to male sprague-dawley rats. Int J Basic Clin Pharmacol 2018;7:93-7
Bissenova S, Ellis D, Mathieu C, Gysemans C. Neutrophils In Autoimmunity: When The Hero Becomes The Villain. Clin Exp Immunol. 2022; 210 (2):128-140.
Pérez-Figueroa E, Álvarez-Carrasco P, Ortega E, Maldonado-Bernal C. Neutrophils: Many Ways to Die. Front Immunol. 2021 Mar 4;12:631821.
Mims MP, Hoffman R, Benz EJ Jr., Silberstein LE, Heslop HE, Weitz JI, Anastasi J, Salama ME, Abutalib SA, Hematology. 2018. 682–690 p
Encaiova G, Dapoto K, Zimmermann R, Krafft A. Red blood cell parameters in antenatal nonsickling hemoglobinopathy screening. Int J Womens Health. 2015; 7: 379-84.
Mandrile G, Barella S, Giambona A, Gigante A, Grosso M, Perrotta S, Scianguetta S, Forni GL. First and Second Level Haemoglobinopathies Diagnosis: Best Practices of the Italian Society of Thalassemia and Haemoglobinopathies (SITE). J Clin Med. 2022;11(18):5426.
Ki YJ, Park S, Ha SI, Choi DH, Song H: Usefulness of mean platelet volume as a biomarker for long-term clinical outcomes after percutaneous coronary intervention in Korean cohort: a comparable and additive predictive value to highsensitivity cardiac troponin T and N terminal pro-B type natriuretic peptide. Platelets 2013. Epub ahead of print.
Engelbrecht M, Atkinson B, Goddard A, Pazzi P, McClure V. Mean Platelet Volume and Platelet Volume Distribution Width in Canine Parvoviral Enteritis. Front Vet Sci. 2021;8:722280.
Korniluk A, Koper-Lenkiewicz OM, Kamińska J, Kemona H, Dymicka-Piekarska V. Mean Platelet Volume (MPV): New Perspectives for an Old Marker in the Course and Prognosis of Inflammatory Conditions. Mediators Inflamm. 2019; 2019: 9213074.
Barale C, Russo I. Influence of Cardiometabolic Risk Factors on Platelet Function. Int J Mol Sci. 2020 Jan 17;21(2):623.
Tang J, Gao X, Zhi M, Zhou HM, Zhang M, Chen HW, Yang QF, Liang ZZ. Plateletcrit: a sensitive biomarker for evaluating disease activity in Crohn's disease with low hsCRP. J Dig Dis. 2015 Mar;16(3):118-24.
Iida H, Kaibori M, Matsui K, Ishizaki M, Kon M. Ratio of mean platelet volume to platelet count is a potential surrogate marker predicting liver cirrhosis. World J Hepatol. 2018 Jan 27;10(1):82-87.
Uddin MA, Akter F, Chowdhury IH, Asha UH, Tanny SZ, Sony TA, Neon N, Saha N, Sikder MM, Yesmine S Toxicological studies of Leaf extract of Stevia rebaudiana Bertoni in Sprague-Dawley Rats. Trop J Nat Prod Res. 2022; 6(5): 714-720
Nilesh M, Harshad G, Samir G, Sunanda B, Amit N Preparation and Analytical Study of Vata Gajendra Singh Rasa. nt. J. Ayur. Pharma Research, 2016;4(2):33-41
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