Phytochemical Screening and Antioxidant Activity of Longevity Remedy from National Thai Traditional Medicine Scripture (Formulary Special Edition)
doi.org/10.26538/tjnpr/v6i6.6
Keywords:
Antioxidant, Flavonoids, Longevity,, Phenolic compounds, Thai traditional medicineAbstract
A longevity remedy from Thai traditional medicine (formulary special edition) has been linked to body health nourishment, appetizing, muscle pain relief, relaxation, normal excretion, body health improvement, and, most importantly, long-life aging. This longevity remedy has been described to possess anti-aging properties, however, there is no scientific justification to support this. The present study was therefore aimed at conducting a phytochemical screening and evaluating the antioxidant activities of the longevity remedy from Thai traditional medicine (formulary special edition). The wood of Streblus asper, Diospyros rhodocalyx, and Albizia procera, as well as Tinospora cordifolia vine, Piper nigrum fruits, and Cyperus rotundus were formulated into longevity remedy. Aqueous, hydro-ethanol, and ethanol extracts were prepared from the longevity remedy. In a phytochemical screening, total phenolic content (TPC) and total flavonoid content (TFC) were measured. The antioxidant activities were examined by 2,2-diphenyl-1-picrylhydrazy (DPPH), 2,2-azinobis-(3-ethylbenzothiazoline-6-sulphonate) (ABTS+ ) radical scavenging, and ferric reducing antioxidant power (FRAP) assays. The results revealed that the 50% ethanol extract contained high amounts of TPC (3.617±0.763 mgGE/gExt) and TFC (5.132±0.082 mgQE/gExt). Furthermore, DPPH (IC50 = 0.0323±0.0008 mg/mL), ABTS (IC50 = 0.0159±0.0004 mg/mL), and FRAP (10.013±0.810 mgTE/gExt) activities were scavenged by this extract according to the techniques used. The findings of this study confirmed the composition of this remedy with TPC and TFC in which it plays a protective role in antioxidant activities.
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